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PhD fellowship in translational fibrosis research / life sciences (f/m/d)

Medizin 3
25.025 hours
Fixed term of 36 months
as of 01.03.2025
Eingruppierung gemäß TV-L
Application deadline 15.02.2025
Universitätsklinikum Erlangen
Medizinische Klinik 3 - AG Bergmann
Dr. med. Christina Bergmann 
Ulmenweg 18
91054 Erlangen

Contact person
Dr. med. Christina Bergmann 
Senior Physician 
Phone: 09131 85 43114
PhD fellowship in translational fibrosis research / life sciences (f/m/d)
Published since: 16.12.2024
Job-Id: 9573
Dr. med. Christina Bergmann 
Senior Physician 
Phone: 09131 85 43114
Universitätsklinikum Erlangen
Medizinische Klinik 3 - AG Bergmann
Dr. med. Christina Bergmann 
Ulmenweg 18
91054 Erlangen

PhD fellowship in translational fibrosis research / life sciences (f/m/d)
Published since: 16.12.2024
Job-Id: 9573
Universitätsklinikum Erlangen
Medizinische Klinik 3 - AG Bergmann
Dr. med. Christina Bergmann 
Ulmenweg 18
91054 Erlangen

Contact person
Dr. med. Christina Bergmann 
Senior Physician 
Phone: 09131 85 43114

Sounds interesting?
Who we are:

We are an international and dynamic laboratory for translational fibrosis research. Our overarching aim is to delineate molecular mechanisms of tissue remodelling in fibrosing disorders as basis for novel therapeutic strategies. Systemic Sclerosis is our central model disease. We have a strong translational focus, which is also reflected in the tight collaboration of scientists and physician scientists within the group.  Group leaders have more than 10 years clinical and scientific experience in the field and we cooperate with national and international partners in academics. 

Your tasks:

We are looking for a highly motivated PhD student (f/m/d) to work on a project focusing on mechanisms of tissue remodeling in Systemic Sclerosis as fibrosing model disease. Fibrosing diseases impose major socioeconomic burdens on modern societies and account for up to 45% of deaths in the developed world. Despite the huge medical need and first approved therapies the morbidity and mortality remain very high. New treatment options such as CD19.CART therapy offer new ways of deep immunosuppression. In this project we aim to characterize the mechanisms of CD19 mediated tissue remodeling compared to state-of-the art treatments. 

The student (f/m/d) will work on established state-of the art techniques of molecular biology including immunofluorescence, RNA seq, Western blot, nucleofection and  siRNA, reporter assay, ChIP assay. The student will also be involved in establishing novel analysis and imaging methods. Working with mouse experiments is optional. 

Essential experience/ qualifications:

  • Graduation at a Master´s level (or equivalent) in biological or biomedical sciences with convincing results
  • Strong interest in biomedical research, in discovering new fields and establishing novel techniques 
  • Strong interest to work both independently and co-operatively within an international
    research team
  • At least basic bioinformatic knowledge 
  • Good written and spoken English skills 

Additionally beneficial are:

  • experience in state of the art techniques of molecular biology and cell culture  

We offer

  • Excellent resources including a fully-equipped laboratory for conducting experiments with state of the art in-vitro and in-vivo techniques of molecular biology
  • Access to a variety of imaging modalities in the Optical Imaging Center Erlangen (OICE), access to core units next Next Generation Sequencing, imaging mass cytometrie unit (CyTOF), among others
  • An empowering work environment embedded in the scientific infrastructure of the Department of Medicine 3 and University Hospital Erlangen 
  • Structured mentoring by experienced principal investigators and the PI board of Medicine 3 
  • Structured Graduation programs (Life@FAU)
  • Interactions within a cooperative network in Department Medicine 3, Friedrich-Alexander Universität Erlangen 
    and national and international cooperating partners   

All benefits at UKER

Working at UKER

We are one of the best hospitals in Germany and one of the largest employers in Middle Franconia. Our success is down to the dedication and daily efforts of our more than 9,600 highly qualified employees in a wide range of different professions. We at Universitätsklinikum Erlangen appreciate that each and every one of our employees are important if we are to continue to provide cutting-edge medicine, conduct excellent research and offer patient care at the highest possible standard.

We look forward to hearing from you if you looking for a job that makes a valuable contribution to society and you are excited about the opportunity to shape cutting-edge medical care with us now and in the future!

Required vaccinations   Our culture

Sounds good? Then you’re likely to fit in well with our team.

apply now

 

Working at the cutting-edge of medicine

Meaningful and essential

Career prospects

Advantages of a collective bargaining agreement


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