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Modernste Medizin und Pflege - mit Sicherheit! Das Universitätsklinikum Erlangen bietet seit seiner Gründung im Jahr 1815 Medizin auf höchstem Niveau. In Diagnose und Therapie werden neueste Erkenntnisse der medizinischen Forschung sowie modernste Geräte eingesetzt. Über 9.000 Mitarbeitende aus rund 50 Berufen sind für die Erfüllung der vielfältigen Aufgaben des Universitätsklinikums Erlangen notwendig und kümmern sich rund um die Uhr um unsere Patienten.

PhD student (m/f/x)


for the Department of Transfusion Medicine and Hemostaseology

Your tasks:

The Department of Transfusion Medicine and Hemostaseology is offering a PhD position starting early in 2022. The project aims to identify early markers of immunodysfunction in systemic inflammation with a focus on sepsis and severe injuries. Furthermore, potential therapy mechanisms targeting neutrophil dysfunction (e.g., modulation of NHE1) will be addressed.
Scope of the project

  • Characterization of neutrophil functions in vitro after stimulation with sepsis related mediators
  • Linking of granulocyte (dys-)function with early cellular markers as certain antigens or intracellular alterations
  • Advancement of a whole blood environment simulating sepsis, e.g., improvement of an already established ex vivo whole blood model
  • Translational application of the identified markers in experimental and clinical sepsis
  • Development of a rapid, clinically applicable method to stratify the risk of patients with related to the function of the immune system
  • Project-related publications (PMIDs): 32958893, 33178198, 33796110


Essential experience/qualifications:

  • Master or equivalent degree in life sciences, including molecular medicine, biochemistry, biology, or bioinformatics
  • Solid knowledge of basic laboratory methods (ELISA, Western Blot, qPCR …)
  • “can-do” attitude with a high motivation combined with the desire to work in an interdisciplinary team of scientists, physicians, students, and post-docs
  • Bioinformatic skills and/or experience in flow cytometry and/or cell sorting are advantageous
  • Proficiency in English, another language is beneficial


Additionally beneficial are:

  • Benefical for international applicants: Proven ability to work in an international environment (e.g., an internship >3-6 months abroad)


Comments:

  • Intended pay grade depending on qualifications and personal requirements according to TV-L E13 (50%)
  • The position is initially for a fixed term of three years, with possibility of extension
  • The starting date is 01.03.2022, or as soon as possible.
  • Application deadline ends on 31.01.2022
  • Notes for applicants (f/m/x)


We offer:

  • secure, interesting job in a motivated, open-minded team
  • Careful and qualified training and support for the new challenge
  • A varied and responsible field of activity with individual development opportunities
  • Comprehensive health promotion offers
  • All benefits of the public service incl. supplementary pension plan of the Versorgungsanstalt des Bundes und der Länder (VBL) (Federal and State Government Employees' Retirement Fund)
  • Family-friendly environment and, where appropriate, places in a dormitory
  • Crediting of work experience possible


Further information:

apl. Prof. Dr. med. Robert Zimmermann
Phone: 09131 85- 36972

Applications:

Applications:
Your application should contain the following documents (merged as one PDF file):
1. Motivation letter
2. Curriculum vitae
3. Copy of diploma(s)
4. Other relevant documents or certificates or letters of recommendation

Please address the applications to:
Universitätsklinikum Erlangen
Transfusionsmedizinische und Hämostaseologische Abteilung
in der Chirurgischen Klinik
Prof. Dr. H. Hackstein, MBA
Krankenhausstraße 12
91054 Erlangen
E-Mail: trans-sekretariat@uk-erlangen.de

Please note that presentation costs can unfortunately not be covered.
UK Erlangen II
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